That sense of hopeless resignation may help us understand the feelings of the Hebrew people during their 400 years of bondage in Egypt. When Moses told them of God’s promise to release them from slavery, they didn’t listen to him “because of anguish of spirit” (Ex. 6:9). They were so far down they couldn’t look up.
But God did something for them that they could not do for themselves. The Lord’s miraculous deliverance of His people foreshadowed His powerful intervention on our behalf through His Son Jesus Christ. It was when “we were powerless to help ourselves that Christ died for sinful men” (Rom. 5:6).
When life is at its lowest ebb, we are not without hope because of the wonderful grace of God.

No one is hopeless whose hope is in God.
(RBC)